Bruton's tyrosine kinase in complex with compound 6
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Bruton's tyrosine kinase in complex with compound 6 Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-~{tert}-butyl-~{N}-[[4-(7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl]benzamide, DIMETHYL SULFOXIDE, ... Authors: Metrick, C.M, Marcotte, D.J. Deposit date: 2020-02-29 Release date: 2020-12-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases. J.Med.Chem., 63, 2020
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2020-02-29
