C57BL6 mice were grafted with GL261-Dsred gliomas cells. One week after graft, 20 mg/ml of SMg was intra-veneously injected. treatment was performed once a week.
Data was measured at the final day of Phase I (24th day) and Phase III/3 (23rd day). a Directly measured data (tumor length, tumor width, tumor mass) b Estimated data (tumor volume measured by caliper
This excel file contains all raw tumor growth measurements and graphs for in vivo efficacy evaluation (Fig 8). This file also contains the compiled exposure times generated for Fig 10.