Summary of absolutely conserved lysine residues and predictions for monoubiquitylation candidates in human Hippo pathway proteins.

aIf only one conserved lysine is present, then we consider it a monoubiquitylation candidate. If multiple conserved lysines are present, then we identify a candidate for monoubiquitylation (underlined). Qualitative assessment of the likelihood that the lysine is monoubiquitylated is indicated (strong or modest).bAbsolutely conserved amino acids surrounding the candidate lysine (underlined) are shown. If amino acids are separated by a slash then that position is variable and the amino acids present are shown. A hydrophobic amino acid (I, L, V or M) in the -1 or -2 position is shown in bold.