PylRS C-terminus domain mutant bound with D-3-bromophenylalanine and AMPNP

NIAID Data Ecosystem2026-05-10 收录

蛋白质-配体共结晶

非天然氨基酸

数据链接：

https://www.rcsb.org/structure/8KE4 数据链接链接失效反馈

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资源简介：

PylRS C-terminus domain mutant bound with D-3-bromophenylalanine and AMPNP

创建时间：

2026-03-04

非天然氨基酸力场数据集

非天然氨基酸

重力场数据

随着基因密码子扩展技术、代谢工程及动态调控策略的不断发展，非天然氨基酸将在合成生物学中发挥更核心的作用，推动生物制造、医疗健康及环境科学等领域的创新突破。其用途主要体现在功能拓展、结构优化、动态调控及新型生物系统构建等方面。通过计算模拟，将非天然氨基酸放入蛋白质元件的微环境中，考察非天然氨基酸插入对蛋白质元件结构与功能的影响。为了达到这一目标，分别采取经验打分函数（Rosetta力场）与量子化学模

国家基础学科公共科学数据中心240

AARS competition data for unnatural amino acids

底物特异性

非天然氨基酸

aAnalog abbreviations are taken from ref. 11. Structures of all analogs are listed in the subsequent tables.b% Inhibition is the average loss in intensity of the AA-AMP peak relative to a control with

Figshare2015-12-02 更新60

Stable Right- and Left-Handed Peptide Helices containing C α -Tetrasubstituted α-Amino Acids

肽模拟物

非天然氨基酸

Short peptidomimetics with stable secondary structures in solution are of interest for applications in chemistry, biology, and medicine. One way to rigidify the backbone of a peptide is the use of cyc

NIAID Data Ecosystem40

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A07a

蛋白质-配体共结晶

片段筛选

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A07a Descriptor: (2-aminopyridin-3-yl)methanol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Auth

Protein Data Bank Japan2024-03-06 更新120

Primary structure of S1 and its analogues.

肽类结构表征

非天然氨基酸

a Nal = β-naphthylalanine Primary structure of S1 and its analogues.

NIAID Data Ecosystem50