Human PRMT5:MEP50 structure with Fragment 1 and MTA Bound
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Human PRMT5:MEP50 structure with Fragment 1 and MTA Bound Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 6-bromo-1H-pyrrolo[3,2-b]pyridin-5-amine, ... Authors: Gunn, R.J, Lawson, J.D, Smith, C.R. Deposit date: 2022-05-12 Release date: 2022-10-05 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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2022-05-12
