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A non-canonical p53–SMPD1 axis drives early sphingolipid dysregulation and lipotoxicity in doxorubicin-induced cardiomyopathy

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Figshare2026-01-23 更新2026-04-28 收录
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A DOX-induced cardiomyopathy model was established in Syrian hamsters via a cumulative dosing regimen. Heart tissues were collected from these hamsters for subsequent metabolomics analysis. Transcriptomics analyses were performed in cellular systems.

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2026-01-23
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