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Refining Colorectal Cancer Classification and Clinical Stratification Through a Single-Cell Atlas

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NIAID Data Ecosystem2026-05-02 收录
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To determine and dissect the extent of tumor, immunological, and stromal heterogeneity in CRC patients, we performed droplet-based scRNA-seq on 16 racially diverse, treatment naïve CRC patient tissue samples and seven adjacent normal colonic tissue samples (totaling 23 samples), yielded 49,589 single cells enabling high-resolution depiction of the cellular diversity and heterogeneity within the tumor and microenvironmental cells.

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2025-02-14
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