Iodide-Mediated Synthesis of Spirooxindolo Dihydrofurans from Iodonium Ylides and 3‑Alkylidene-2-oxindoles
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An iodide-mediated reaction between cyclic iodonium ylides of 1,3-dicarbonyls and 3-alkylidene-2-oxindoles results in 3H-spiro[furan-2,3′-indolin]-2′-ones. The reaction was tolerant to substitutions on both the alkylidene and ylide substrates and provided access to 19 new, densely functionalized polycyclic spirocycles in typically high yield.
创建时间：
2017-07-27
