GERDH

Here, we introduce GERDH (https://dphdatabase.com), a database platform for cross-species data mining among horticultural plants, based on 12 961 uniformly processed publicly available omics libraries from more than 150 horticultural plant accessions, including fruits, vegetables and ornamental plants. Important and conserved genes that are essential for a specific biological process can be obtained by cross-species analysis module with interactive web-based data analysis and visualization. Moreover, GERDH is equipped with seven online analysis tools, including gene expression, in-species analysis, epigenetic regulation, gene co-expression, enrichment/pathway and phylogenetic analysis. By interactive cross-species analysis, we identified key genes contributing to postharvest storage. By gene expression analysis, we explored new functions of CmEIN3 in flower development, which was validated by transgenic chrysanthemum analysis. We believe that GERDH will be a useful resource for key gene identification and will allow for omics big data to be more available and accessible to horticultural plant community members.本文介绍GERDH（官网：https://dphdatabase.com）——一款面向园艺植物的跨物种数据挖掘数据库平台。该平台基于12961个经过统一处理的公开组学文库构建，数据来源于150余个园艺植物种质资源，涵盖果树、蔬菜与观赏植物。借助搭载交互式网页数据分析与可视化功能的跨物种分析模块，可获取特定生物学过程所需的重要保守基因。此外，GERDH配备了七大在线分析工具，涵盖基因表达分析、种内分析、表观遗传调控分析、基因共表达分析、富集/通路分析以及系统发育分析。通过交互式跨物种分析，本研究鉴定出了参与采后贮藏过程的关键基因；通过基因表达分析，本研究揭示了CmEIN3在花发育过程中的新功能，并通过转基因菊花实验验证了该功能。我们认为，GERDH将成为关键基因鉴定的宝贵资源，同时可推动组学大数据更便捷地向园艺植物研究群体开放与共享。

搜集汇总

背景与挑战

背景概述

GERDH是一个园艺植物跨物种数据挖掘数据库平台，整合了来自150多个园艺植物品种的12961个统一处理的公开组学库，涵盖水果、蔬菜和观赏植物。该平台提供七种在线分析工具，包括基因表达、跨物种分析和系统发育分析等，支持关键基因识别，促进组学大数据在园艺植物研究中的可访问性。