Topological domains are key architectural building blocks of chromosomes in complex genomes. Their functional importance and evolutionary dynamics are however not well defined. Here we performed comp
This data repository includes dataset generated from IMR-90, GM12878 cell lines and C.Origami pre-trained model weights. GitHub page: https://github.com/tanjimin/C.Origami
This file contains the source data for Extended Data Figure 1c. c, Hi-C matrix (at 5 kb resolution) and loops at the MRR1 region showing two looping silencers (S1 and S2) that exhibit chromatin intera
