Crystal structure of human Mps1 (TTK) C604W mutant in complex with Cpd-5
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Crystal structure of human Mps1 (TTK) C604W mutant in complex with Cpd-5 Descriptor: 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide Authors: Hiruma, Y, Joosten, R.P, Perrakis, A. Deposit date: 2017-06-15 Release date: 2017-07-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures. J. Biol. Chem., 292, 2017
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2017-06-15
