Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
Estrogens have been shown to elicit anti-cancer effects against estrogen receptor alpha (ER)-positive breast cancer. We sought to determine the underlying mechanism of therapeutic response. Response to estrogen treatment was assessed in ER+ breast cancer models of anti-estrogen resistant disease: WHIM16 patient-derived xenografts, C7-2-HI and C4-HI murine mammary adenocarcinomas, and long-term estrogen-deprived MCF-7 cells.
创建时间：
2018-10-20
