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This is the SELEX sequencing data that would allow for the replication of the data in the ProtSeq manuscript.
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创建时间：
2021-09-27
相关数据集
Systematic Study of in vitro Selection Stringency Reveals How to Enrich High-Affinity Aptamers
Library-immobilized SELEX was performed with an N30 stem-loop structured DNA library to isolate an aptamer that binds to the small molecule flunixin. Pools from various trials were sequenced.
NIAID Data Ecosystem50
IL 6 fold values for all contrasts.
The development of aptamers has been almost exclusively performed based on the SELEX method since their inception. While this method represents a powerful means of harnessing the in vitro evolution of
Figshare2025-02-12 更新30
A compendium of the aptamers obtained by selection vs cancers TOV-21G (aptTOV) or CAOV-3 (DOV).
A compendium of the aptamers obtained by selection vs cancers TOV-21G (aptTOV) or CAOV-3 (DOV).
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Selection and targeting of EpCAM protein by ssDNA aptamer
Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small
NIAID Data Ecosystem50
Investigating the Influences of Random-Region Length on Aptamer Selection Efficiency Based on Capillary Electrophoresis–SELEX and High-Throughput Sequencing
For aptamer selection, the random-region length of an ssDNA library was generally taken in a relatively arbitrary fashion, which may lead to failure for unsuitable target binding. Herein, we coupled h
NIAID Data Ecosystem20
