GLP-1 reduced pro-fibrotic molecules in HF- or HG-stimulated cardiomyocytes.
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(a) GLP1R expression in the GK model (left) (n=5, each group), and HL-1 stimulated cardiomyocytes (right). A representative QPCR-amplification plot of each rat or stimulated cell is also showed. (b) Intracellular (by WB and IF) and (c) secreted levels of fibronectin (FN) in GLP-1-pre-treated cardiomyocytes exposed to HF (0.25 mM) or HG (33 mM). (d) Pro-fibrotic expression (TGFß1 and CTGF) in stimulated cardiomyocytes. *p
创建时间：
2016-02-24
