We report the mutation profile of measles F gene by saturating mutagenesis. We evaluate the mutation rate of measles F gene in pCDNA3 backbone (shuttle plasmid), pEMC backbone (genome plasmid), and RT
We directly estimated the spontaneous mutation rate and the mutational spectrum in the non-biting midge C. riparius with a new approach. Individuals from ten mutation accumulation lines over five gene
Mutations are the raw material on which evolution acts, and knowledge of their frequency and genomic distribution is crucial for understanding how evolution operates at both long and short timescales.
Cancer is the result of the accumulation of mutations in the DNA of somatic tissue during the lifetime of an organism. Therefore, animals that live longer and/or have a larger number of cells should h