Transcriptomic analysis of primary human lung cells and tissue samples highlights cellular crosstalk during infections with influenza A virus

We used RNA sequencing to comprehensively map the expression of coding and non-coding RNAs in primary human alveolar epithelial type II cells (AECIIs), alveolar macrophages (AMs), human lung tissue, and the epithelial cell line A549 during infection with IAV strain H3N2 Panama Infected and uninfected samples of each cell type were compared in biological triplicates.