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Epithelial NAD+ Depletion Drives Mitochondrial Dysfunction and Contributes to Intestinal Inflammation

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NIAID Data Ecosystem2026-05-01 收录
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NAD+ metabolism and PGC1a expression with the intestinal epithelium play a significant role in the development and progression of intestinal inflammation. Modulating cellular NAD+ levels with NAD+ precursors enhances mitochondrial function through the PGC1a axis in murine models of experimental colitis.

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2023-07-11
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