Human PRMT5:MEP50 structure with Fragment (Example 18) and MTA Bound
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Human PRMT5:MEP50 structure with Fragment (Example 18) and MTA Bound Descriptor: 3-ethylimidazo[4,5-b]pyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ... Authors: Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. Deposit date: 2022-05-12 Release date: 2022-10-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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2022-05-12
