Background: Sex chromosomes evolve from an autosomal pair after the acquisition of a sex-determining gene. The primary sex chromosomes are homomorphic in both sexes and often undergo heteromorphism in

DataCite Commons2025-05-01 更新50

Additional file 4: of Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum

染色体结构变异

真菌次级代谢遗传

Table S2. Large inversions identified with NUCmer. (XLXS 21.8 kb)

NIAID Data Ecosystem40

Mutational signatures reveal the role of RAD52 in p53-independent p21 driven genomic instability

基因组不稳定性

突变体分析

Genomic instability promotes evolution and heterogeneity of tumors. Unraveling its mechanistic basis is essential to design appropriate therapeutic strategies. In a recent study we reported an unexpec

NIAID Data Ecosystem90

Drosophila salivary gland imaginal ring tumor single cell DNA copy number variation (CNV)

基因组不稳定性

拷贝数变异分析

Variation and heterogeneity in ploidy are general features of human cancers. This variation can be an increase of the number of chromosome set (polyploidy), an increase or decrease of a small numbers

NIAID Data Ecosystem40

The GCR rate of cells with extra copies of SLD2.

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