Retinal astrocyte transcriptome reveals an important role for Cyp1b1 expression in modulation of cell adhesive and migratory properties

Global genome-wide sequencing analysis of RNA prepared from Cyp1b1-/-AC and Cyp1b1+/+AC was performed to gain additional insight into the cellular regulatory mechanisms impacted by Cyp1b1 expression Transcriptome comparison between Cyp1b1-/- retina astrocytes vs Wt retina astrocytes为深入阐明Cyp1b1基因表达所影响的细胞调控机制，本研究对源自Cyp1b1基因敲除型视网膜星形胶质细胞（Cyp1b1-/-AC）与野生型（Wild type, Wt）视网膜星形胶质细胞（Cyp1b1+/+AC）的RNA样本开展了全转录组测序分析，并对两组样本的转录组进行了对比研究。