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A Domino Annulation Reaction under Willgerodt−Kindler Conditions

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NIAID Data Ecosystem2026-03-06 收录
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Butanone side chains at arenes and hetarenes, efficiently introduced by a Heck-type reaction, are transformed to annulated thieno[3,2-b]thiophenes in a domino redox process under Willgerodt−Kindler conditions. A nucleophilic aromatic substitution with an intermediary thioenolate is a reasonable key step of this process.

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2016-02-27
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