ATC is a very rare, but extremely aggressive form of thyroid malignancy, responsible for the highest mortality rate registered for thyroid cancer. In the patients without known genetic aberrations, th
We evaluated the in vitro pharmacology as well as the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of chemical entities that not only were shown to be highly select
Anaplastic thyroid cancer (ATC) is one of the most aggressive cancers characterized with extremely rapid growth rate. Dysregulation of RNA polymerase (Pol) is critical for cancer development, but litt
