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Triazine mechanism of action in M. tuberculosis

NIAID Data Ecosystem2026-04-25 收录

结核分枝杆菌耐药性

药物靶点识别

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP185461 数据链接链接失效反馈

官方服务：

资源简介：

Whole genomic sequencing reads were collected from M. tuberculosis resistant mutants for target identification

应用场景：

创建时间：

2020-02-07

结核分枝杆菌耐药性

药物转录组学

Transcriptional profiling of Mycobacterium tuberculosis CDC1551 and 6-azasteroid resistant mutants ASR1 and ASR2 with treatment of 6-azasteroids, 4a and 6a, for 6 hours. Overall design: Three differen

NIAID Data Ecosystem10

Structure of S70C BlaC from Mycobacterium tuberculosis

结核分枝杆菌耐药性

蛋白质结构解析

Structure of S70C BlaC from Mycobacterium tuberculosis

NIAID Data Ecosystem00

Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae

蛋白质晶体学

药物靶点识别

Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae

NIAID Data Ecosystem00

Orbifloxacin-resistant Mtb H37Ra Genome sequencing and comparsion with wild type. Mycobacterium tuberculosis H37Ra strain:ATCC-25177

结核分枝杆菌耐药性

抗结核药物靶点鉴定

To figure out the anti-M.tb mechanism of orbifloxacin, we obtained an orbifloxacin-resistant M.tb strain and revealed the drug target gene by whole-genome sequencing. A critical point mutation (Gyrase

NIAID Data Ecosystem10

Example network equations in text format from Therapeutic target discovery using Boolean network attractors: improvements of kali

布尔建模

药物靶点识别

The equations of the example network in text format.

Figshare2018-01-27 更新00