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Cryo structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 3 hours

NIAID Data Ecosystem2026-05-02 收录

药物靶点结构

结核病耐药性

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Cryo structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 3 hours

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创建时间：

2024-11-20

结核病耐药性

纳米孔测序

TB seek is a new nanopore sequencing based test designed for simultaneous TB identification and antibiotic resistance genotyping. The TBseek test is based on multiplex PCR, targeting specific genes fo

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Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT416

结核病耐药性

结构生物学药物发现

Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT416 Descriptor: DIMETHYL SULFOXIDE, N,N-diethyl-2-[(8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl

Protein Data Bank Japan2023-10-11 更新40

Genomic variants associated with an increase of BDQ MIC ≥ 0.12 μg/mL.

结核病耐药性

药物基因组学

Genomic variants associated with an increase of BDQ MIC ≥ 0.12 μg/mL.

Figshare2025-07-15 更新20

Transmitted Extended-spectrum XDR Tuberculosis in Beijing

结核病耐药性

基因组与表观基因组学

Drug-resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum XDR (XXDR) tuberculosis, resistant to most first and second-line agents. Correlatio

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Genetic Determinants of Isoniazid and Rifampicin resistance in Mycobacterium tuberculosis in Southern India

结核病耐药性

微生物基因组学

There is an urgent need to understand the mechanisms by which the mutations confer resistance in order to design new drugs and to identify new drug targets. Previous studies have reported numerous mut

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Cryo structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 3 hours

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