Direct Solvent-Free Regioselective Construction of Pyrrolo[1,2‑a][1,10]phenanthrolines Based on Isocyanide-Based Multicomponent Reactions
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资源简介：
A novel efficient one-pot four-component regioselective synthesis of pyrrolo[1,2-a][1,10]phenanthrolines in excellent yields has been developed by 1,3-dipolar cycloaddition of aldehydes, malononitrile, and isocyanides with 1,10-phenanthroline under solvent-free conditions within 3 min without using any catalyst or activation. The products were preliminarily investigated as chromogenic and fluorescent sensors for Cu2+ ions.
创建时间：
2016-02-19
