Med1 is Necessary for Cardiac Function

Name: Med1 is Necessary for Cardiac Function
Creator: Gene Expression Omnibus
Published: 2026-07-23T07:52:24+08:00

DataMed2026-07-23 收录

心脏疾病分子机制

扩张型心肌病

数据链接：

https://datamed.org/dataset/ba95cc3f-1a1b-4524-8321-36bd66df00c7 数据链接链接失效反馈

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资源简介：

Analysis of ventricular derived mRNA from Med1fl/fl and Med1fl/fl cardiac knockout mice. Results provide insight into the molecual rmechanisms underlying dilated cardiomyopathy.

提供机构：

Gene Expression Omnibus

A context-specific cardiac Beta-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. A context-specific cardiac Beta-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart

心脏疾病分子机制

表观遗传与转录调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem80

Additional file 2: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

心力衰竭转录组学

心脏疾病分子机制

Table S2. RNAseq quality control table. Raw read counts ranged from ~â 36 to 66 million. Read counts show a 99% retention after base quality control and a 94â 96% alignment rate. (XLSX 16Â kb)

Figshare2018-11-13 更新60

Distinct TCF7L2 genomic occupancies discern chromatin states in the neonatal and diseased mammalian myocardium [RNA-Seq]

器官再生研究

心脏疾病分子机制

In mammals, Wnt pathway is activated during both heart regeneration post-injury and disease. Our previous work described the role of nuclear Wnt effectors B-catenin and Transcription factor 7-like 2 (

NIAID Data Ecosystem50

Inhibition of BRD4 Rescues Cardiac phenotype in Myocyte-Specific Lamin A/C Null Mice

心脏疾病分子机制

基因治疗研究

Deletion of Lmna, encoding nuclear membrane protein LMNA, specifically in mouse cardiac myocytes activates BRD4 and leads to heart failure, arrhythmias, myocardial fibrosis, apoptosis, and premature d

NIAID Data Ecosystem60

Clinical characteristics of the patients with dilated cardiomyopathy whose tissues were examined by RNA-Seq and western blot analyses.

扩张型心肌病

生物学分析

Clinical characteristics of the patients with dilated cardiomyopathy whose tissues were examined by RNA-Seq and western blot analyses.

NIAID Data Ecosystem50