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Enantioselective Synthesis of Functionalized Medium-Sized Oxacycles

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NIAID Data Ecosystem2026-03-06 收录
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Enantioselective routes to functionalized, seven-, eight-, and nine-membered oxacycles that are amenable to further elaboration have been developed. Salient features of the methodology include highly diastereoselective and regioselective transformations of an ephedrine-derived epoxy morpholinone to functionalized precursors of the oxacycles. The ephedrine scaffold exerts remote stereocontrol in the functionalization of the appended oxacycle.

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2016-02-29
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