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Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention.

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NIAID Data Ecosystem2026-03-12 收录
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We report the application of RNA sequencing technology for high-throughput profiling of both host and human cytomegalovirus (HCMV) transcript levels in latenly infected CD14+ monocytes after treatment with histone deacetylase inhibitors (CHR-4487) and BET-bromodomain inhibitors (GSK726). Examination of changes to the HCMV latent transcriptome with epigenetic inhibitor treatment.

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2021-03-02
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