pVanessa/Tahoe-100M

Tahoe-100M 是一个千兆级别的单细胞扰动图谱，包含超过1亿个转录组谱，这些数据来自50个癌细胞系暴露于1,100个小分子扰动的实验。该数据集利用Vevo Therapeutics的Mosaic高通量平台生成，能够在前所未有的规模和分辨率下，深入、上下文感知地探索基因功能、细胞状态和药物反应。它旨在为下一代细胞生物学AI模型的开发提供支持，在系统生物学、药物发现和精准医学等领域具有广泛的应用前景。Tahoe-100M is a giga-scale single-cell perturbation atlas consisting of over 100 million transcriptomic profiles from 50 cancer cell lines exposed to 1,100 small-molecule perturbations. Generated using Vevo Therapeutics Mosaic high-throughput platform, Tahoe-100M enables deep, context-aware exploration of gene function, cellular states, and drug responses at unprecedented scale and resolution. This dataset is designed to power the development of next-generation AI models of cell biology, offering broad applications across systems biology, drug discovery, and precision medicine.