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Protein Profiling of human iPSC-derived cardiomyocytes with mutations in ACTN2

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NIAID Data Ecosystem2026-03-14 收录
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Genetic variants in α-actinin 2 (ACTN2) are associated with several forms of (cardio)myopathy. Here, we analyzed the proteome of 2D and EHT cultured cardiomyocytes derived from mutant-expressing (ACTN2mut) and a wild-type-expressing (ACTN2wt) hiPSC lines, both created with CRISPR/Cas9 genetic tools.

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2022-10-13
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