TB seek is a new nanopore sequencing based test designed for simultaneous TB identification and antibiotic resistance genotyping. The TBseek test is based on multiplex PCR, targeting specific genes fo
‘*’ resistance determined at amikacin (AMK, 6 μg/ml), kanamycin (KAN, 6 μg/ml) and capreomycin (CAP, 6 μg/ml), ‘wt’ wild type indicates absence of SNPs in the rrs 1400 gene, the number in parenthesis
Drug-resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum XDR (XXDR) tuberculosis, resistant to most first and second-line agents. Correlatio