Singh et al. DDX41 is required for cGAS-STING activation against DNA virus infection. Cell Rep 2022
收藏Mendeley Data2026-04-09 收录
相关数据集
The Cardiac Endothelial Cell cGAS-STING Pathway Promotes Doxorubicin-Induced Cardiotoxicity via CD38-Mediated NAD Decline and Mitochondrial Dysfunction [human]. The Cardiac Endothelial Cell cGAS-STING Pathway Promotes Doxorubicin-Induced Cardiotoxicity via CD38-Mediated NAD Decline and Mitochondrial Dysfunction [human]
Doxorubicin is an effective chemotherapy drug for treating various types of cancer. However, lethal cardiotoxicity severely limits its clinical use. Recent evidence has indicated that aberrant activat
NIAID Data Ecosystem40
BX795 small inhibitor of TBK1 effect on mouse fibroblast cell line that transfected with pEGFP-N1 plasmid
Abstract:DNA transfection is widely used in biomedical research. However, transfection efficiency is often the bottleneck of research and gene therapy practices. To explore the mechanism regulating tr
NIAID Data Ecosystem30
TRPV4 promotes the cGAS-STING signalling pathway in macrophages
This thesis investigates the role of TRPV4, an ion channel protein that contributes to immune responses in the body. TRPV4 is a key player in influencing how macrophages respond to pathogens such as b
Monash University Figshare2026-02-11 更新10
Gene expression profiling of dsDNA-transfected reconstituted mouse embryonic fibroblasts. Mus musculus
Analysis of dsDNA-induced innate immune response at gene expression level. The hypothesis tested in this study was that K224R mutation significantly inhibits hSTING activity. Results provide important
NIAID Data Ecosystem40
Efficacy of small molecule inhibitors and genetic interference of cGAS-STING axis on development of the senescence-associated secretory phenotype (SASP) in human stromal cells
Rapid advancements in next generation sequencing (NGS) have revolutionized system-based analysis of genome-wide expression, cellular pathways and stress responses. We performed this cGAS-STING-associa
NIAID Data Ecosystem10



