Spatial resolution of mobile phone microscopy has improved with mobile phone advancement.

A The spatial resolution of mobile phone microscopy with iPhone and Android phones is plotted as a function of the effective pixel size for images taken with a 10×/0.25 NA objective. The theoretical constraints on resolution imposed by pixel spacing on the Bayer color sensor array are plotted along with the empirically determined resolution limit of the underlying microscope optics. B The spatial resolution of mobile phone microscopy with the same iPhone and Android phones is plotted as a function of megapixel count. C Spatial resolution of the iPhone family of phones is plotted over time, together with the dates of significant camera advancements.