Outcomes (%) by CRP-protocol compliance status.¹

1Compliance with the CRP-protocol in the setting of negative blood cultures was defined as (1) antibiotics were discontinued ≤48 hours after 2 consecutive negative CRP results or continued after at least one positive CRP value [“CRP-protocol compliant” (Comp)], and (2) antibiotics were continued >48 hours despite negative serial CRP results [“CRP-protocol non-compliant” (Non-Comp)]. 2Pearson test. 3Defined as supplemental oxygen requirement ≥36 weeks postconceptional age. 4CONS = Coagulase-negative Staphylococcus.