1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii in complex with a Fosmidomycin analog, NADPH, and a magnesium ion

1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii in complex with a Fosmidomycin analog, NADPH, and a magnesium ion Descriptor: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, CHLORIDE ION, ... Authors: Girma, M.B, Ball, H.S, Belcher Dufrisne, M, Lee, S.H, Soojhawon, I, Noble, S.M, Dowd, C.S, Couch, R.D. Deposit date: 2025-06-05 Release date: 2026-03-25 Last modified: 2026-07-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-Activity Relationships among Inhibitors of Acinetobacter baumannii and Klebsiella pneumoniae 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR/IspC) - A Promising Target for Antibiotic Development. Acs Infect Dis., 12, 2026