Synthetic Access to All Four Stereoisomers of Oxetin
收藏NIAID Data Ecosystem2026-03-09 收录
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A short synthesis of all four stereoisomers of 3-amino-2-oxetanecarboxylic acid (oxetin) is described. The oxetane core is built using a Paternò–Büchi photochemical [2 + 2] cycloaddition; from the key intermediates, complementary resolution protocols provide access to enantiomerically pure oxetin and epi-oxetin on gram-scale.
创建时间：
2016-10-17
