We report the PAMs of diverse type I-E CRISPR- Cas systems and the type I-C and the type I-F1 CRISPR-Cas systems from Xanthomonas albilineans. Furthermore, we report PAMs of two type I-B CRISPR transp
Clostridium autoethanogenum is an industrially relevant anaerobic acetogen that can metabolize C1 substrates to more reduced carbon molecules. The organism natively encodes a type I-B CRISPR system fo
Here we developed BreakTag, a versatile, highly parallel and scissile-aware methodology for the profiling of Cas9-induced DNA double strand break (DSBs), to identify molecular determinants influencing
