Linking CRISPR/Cas9 double-strand break profiles to gene editing precision with BreakTag [cas9_variants]. Linking CRISPR/Cas9 double-strand break profiles to gene editing precision with BreakTag [cas9_variants]
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
Here we developed BreakTag, a versatile, highly parallel and scissile-aware methodology for the profiling of Cas9-induced DNA double strand break (DSBs), to identify molecular determinants influencing Cas9 incisions Overall design: Characterization of the scissile profile of seven previously described engineered variants with reduced off-target activity: HiFiCas9, xCas9, SniperCas9, HypaCas9, EvoCas9 and LZ3Cas9
创建时间：
2023-01-26
