The fundamental methodological deficiency of megatrials is deliberate reduction of experimental control in order to maximize recruitment and compliance of subjects. Hence, typical megatrials recruit p
1—Was the study described as randomized?2—Was the method of randomization described and appropriate?3—Was the study described as double blind?4—Was the method of blinding described and appropriate?5—W
Im Unterschied zu den Arzneimittelstudien gibt es für Studien zur Wirkungsprüfung von psychologischen Therapien keinen verbindlichen methodischen Standard und keine gesetzlichen Regelungen. Dies hat s
