Transcriptional control of amino acid biosynthesis

We transcriptional profiled four transcription factor knockout strains in S288C background growing in YNB media + 2% glucose to understand the link between mRNA levels and our measured C13 fluxes of amino acid biosynthesis. We conducted this analysis as a follow up to our work on the Gcn4p transcription factor. Keywords: genetic modification Multiple biological replicates were conducted for four transcription factor knockout strains