The synthetic small molecule FL3 combats intestinal tumorigenesis via Axin1 inhibition of Wnt/Beta-catenin signaling
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
FL3 is a novel small molecule inhibitor of Wnt/Beta-catenin signaling dependent on PHB1-induced Axin1 expression. The targeting of PHB1 by FL3 provides a novel mechanism to combat Wnt-driven cancers such as CRC with limited intestinal toxicity.
创建时间：
2024-03-10
