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m6A RNA modification controls cell fate transition in mouse embryonic stem cells

ChEBI2014-10-16 更新2026-07-21 收录

RNA表观遗传学

细胞命运调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-52681 数据链接链接失效反馈

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m6A RNA modification controls cell fate transition in mouse embryonic stem cells

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创建时间：

2014-10-16

细胞命运调控

毛囊发育分子机制

In adult K14ΔNLef1 mouse, the overexpression of ∆NLef1, a B-catenin dominat negative, in basal keratinocytes leads to the conversion of hair follicles into multilayered epithelial cysts and ectopic se

NIAID Data Ecosystem60

Oscillations of the p53-Akt Network: Implications on Cell Survival and Death

细胞命运调控

P53信号通路

Intracellular protein levels of p53 and MDM2 have been shown to oscillate in response to ionizing radiation (IR), but the physiological significance of these oscillations remains unclear. The p53-MDM2

NIAID Data Ecosystem40

Additional file 1 of The alteration of N6-methyladenosine (m6A) modification at the transcriptome-wide level in response of heat stress in bovine mammary epithelial cells

RNA表观遗传学

热激应激响应

Additional file 1. m6A peaks in H and NH groups.

Figshare2024-02-07 更新10

Additional file 3 of Dissecting the sequence and structural determinants guiding m6A deposition and evolution via inter- and intra-species hybrids

RNA表观遗传学

种间杂交

Additional file 3: The m6A-peaks detected throughout this study in the yeast strains (Table S3), human-mice interspecies hybrid system (Table S4) and mice-mice intraspecies hybrid system (Table S5).

Figshare2024-08-18 更新60

M6A IP from BrU-labeled and fragmented nascent RNA.

RNA表观遗传学

M6A修饰检测

M6A immunoprecipitation from 15min BrU labeled and fragmented nascent RNA. HEK293T cells were incubated with 2 mM bromouridine for 15 min labeling time (pulse). Whole-cell total RNA was extracted with

NIAID Data Ecosystem30

m6A RNA modification controls cell fate transition in mouse embryonic stem cells

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