CAGE-seq analysis of Fus-knocked down N2A cells. Mus musculus

NIAID Data Ecosystem2026-03-08 收录

FUS基因敲低效应

RNA加工调控

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https://www.ncbi.nlm.nih.gov/bioproject/PRJDB3084 数据链接链接失效反馈

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To analyze role of FUS in RNA processing, CAGE-seq analysis was performed using mouse neuroblastoma cell line, Nuero2A (N2A) cells. N2A cells were treated with Fus-siRNA or control siRNA.

创建时间：

2015-05-15

Additional file 5 of SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

选择性多聚腺苷酸化

RNA加工调控

Additional file 5.

Figshare2021-03-12 更新50

Structural characterization of the 3'-end pre-mRNA processing complex CStF

RNA加工调控

癌症分子机制

The main goal of this proposal is to build a comprehensive understanding of a new layer of eukaryotic 3’-end precursor-mRNA processing, with focus on the Cleavage Stimulation Factor (CStF) complex. Th

DataCite Commons2025-09-28 更新30

Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation [ChrRNA-seq]. Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation [ChrRNA-seq]

癌症分子机制

RNA加工调控

Cleavage and polyadenylation (CPA) defines the 3’ end of almost all eukaryotic mRNAs. CPA inhibition, or CPAi, leads to transcriptional readthrough. Here, we show that the CPSF-73 inhibitor JTE-607 gl

NIAID Data Ecosystem20

Genome-wide Identification of DEAD-box RNA Helicase Targets Reveals Roles for RNA Secondary Structure Remodeling in mRNA Processing (Structure-seq)

RNA二级结构

RNA加工调控

Accurate gene expression requires the coordination of RNA processing with assembly of messenger RNA-protein (mRNP) complex. RNA helicases are a class of enzymes that unwind RNA duplexes in vitro and h

NIAID Data Ecosystem40

MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins Through the Action of the ERH Protein. Fang and Bartel

MicroRNA生物发生

RNA加工调控

Microprocessor initiates processing of microRNAs (miRNAs) from hairpin regions of primary transcripts (pri-miRNAs). Pri-miRNAs often contain multiple miRNA hairpins, and this clustered arrangement can

Mendeley Data2020-04-04 更新30

CAGE-seq analysis of Fus-knocked down N2A cells. Mus musculus

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