Tongue tissue gene profile in 4NQO induced tongue carcinogenesis before and after IL-1Ra interference. Rattus norvegicus

Nine groups of rat tongue tissue RNA samples, including three from normal control, three from 4NQO induced tongue tissue, and three from 4NQO induced and IL-1Ra interference tongue tissue (3 rats per group) were collected for gene microarray hybridization. Overall design: Significant fold changes among genes were determined by taking the ratio of the expression between 4NQO group and 4NQO+IL-1Ra group versus normal control group in epithelia and fibroblasts cells