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A Signaling Lipid Associated with Alzheimerâs Disease Promotes Mitochondrial Dysfunction

ChEBI2016-01-21 更新2026-07-12 收录

阿尔茨海默病病理学

线粒体功能障碍

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40814 数据链接链接失效反馈

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A Signaling Lipid Associated with Alzheimerâs Disease Promotes Mitochondrial Dysfunction

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创建时间：

2016-01-21

阿尔茨海默病病理学

单细胞RNA测序

Neurons located in the layer II of the entorhinal cortex (ECII) are the primary site of pathological tau accumulation and neurodegeneration at preclinical stages of Alzheimer's disease (AD). Exploring

NIAID Data Ecosystem40

Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming

线粒体功能障碍

癌细胞重编程

Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming

ChEBI2015-05-05 更新00

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

tau蛋白播种机制

阿尔茨海默病病理学

Tau is a pathogenic protein in Alzheimer’s (AD) and other neurodegenerative diseases. The misfolding of tau into β-sheet rich elongated filaments is thought to be a key event in disease pathogenesis,

NIAID Data Ecosystem00

Figure 2 and Extended data Figure 2

肝脏代谢稳态

线粒体功能障碍

Raw data for Figure 2 and extended data from the manuscript " Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity."

Figshare2024-04-05 更新10

Table_2_Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer’s disease.DOCX

阿尔茨海默病病理学

tau蛋白清除机制

IntroductionSeverity and distribution of aggregated tau and neurofibrillary tangles (NFT) are strongly correlated with the clinical presentation of Alzheimer’s disease (AD). Clearance of aggregated ta

NIAID Data Ecosystem00

A Signaling Lipid Associated with Alzheimerâs Disease Promotes Mitochondrial Dysfunction

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A Signaling Lipid Associated with Alzheimerâs Disease Promotes Mitochondrial Dysfunction