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Sequencing analysis of immunopanned embryonic and early postnatal mouse RGCs

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We report the genome-wide RNA sequencing changes to isolated retinal ganglion cells (RGCs) from immunopanned embryonic day 18 (E18) and early postnatal (P5) wildtype mouse retinas. We report the transcriptomic change associated with RGCs in a survival and regenerative state, and use gene-set enrichment analysis (GSEA) to predict the upstream transcription factors likely regulating these observed changes. Time-course analysis of RGC transcriptomes in embryonic versus postnatal states.

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