Neuronal plasticity of the inner retina has been observed in response to photoreceptor degeneration. Typically, this phenomenon has been considered maladaptive and may preclude vision restoration in t
The retinal transcriptome of two non-allelic forms of retinitis pigmentosa (RP) in dogs, RCD1 and XLPRA2, was analyzed at clinically relevant advanced stages of the two diseases and compared to that o
Retinitis pigmentosa (RP) is a photoreceptor disease that affects approximately 100,000 people in the United States. There are currently very limited treatment options and the prognosis for most patie
The goal of the study was to identify transcriptional modifications in retinal tissues from mouse model of rhodopsin mutation-associated retinitis pigmentosa (RP), Q344X compared to wild-type (WT). We