Twelve rats were randomly divided into three groups: the expanded group (n = 4), the sham operated group (n = 4), and the normal control group (n = 4). the rats in the expanded group underwent one mil
Total RNA extraction from skin transcriptome was achieved usingTRIzol® Reagent (Life Technologies, Cat. 15596-026) according to themanufacturer's protocol. RNA samples were further purified using RNe
This sub-study investigated the cellular and molecular effects of oral roflumilast treatment on psoriatic skin. Patients with moderate-to-severe psoriasis were allocated 1:1 to monotherapy with oral r