Effect of MODY2 mutations p.Gly223Ser and p.Ala449Thr on the affinity of GK for N-acetylglucosamine (NAG), mannoheptulose (MH) and palmitoyl-CoA.
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Concentrations of inhibitors causing 50% inhibition (I50) were derived from Dixon plots as described in Materials and Methods. Data represent means ± SEM of at least four separate experiments from at least two independent enzyme purifications. (**) pp = 0.03.
创建时间：
2015-12-02
