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Identification and pharmacological evaluation of a bombesin-related pentadecapeptide from the skin secretion of the broad-folded frog, Hylarana latouchii

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NIAID Data Ecosystem2026-03-11 收录
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Ranatensin-HLa is a novel bombesin-like peptide which was isolated from the lyophilised skin secretion of Hylarana latouchii. It was originally-identified through “shot-gun” cloning of its biosynthetic precursor sequence. The synthetic Ranatensin-HLa was found to exhibit potent pharmacological activity on increasing frequency of contraction of rat uterus smooth muscle, and myotropic activity on rat bladder smooth muscle.

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2020-01-08
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